What is biological aging?
The underlying premise of biological aging is that you age as a result of damage to numerous cells and tissues in your body.
Biological age, also known as physiological or functional age, differs from chronological age in that it considers a variety of elements other than the day of birth.
The precise figure depends on a variety of biological and physiological development parameters. Here are a few examples:
- chronological age
- Genetics (how quickly your body’s antioxidant defenses kick in, for example)
- lifestyle
- nutrition
- illnesses and other afflictions
Medical practitioners can figure out what age your body “acts” like it is using these standards and numerous mathematical models.
While chronological age is important, your biological age may differ from your chronological age.
For example, if you’re a 28-year-old male who doesn’t exercise, consumes only high-fat meals, and has smoked five packs of cigarettes every day for the past ten years, your biological age is likely to be higher than 28.
How to Measure Biological Aging
In this article, you can find out about the important biological studies that come with studying aging. You will learn about changes in cells, chromosomes, DNA molecules, and tissues as the body ages.
Studying Chromosomal Instability
Researchers have found that chromosomal instability is caused by DNA damage in the chromosomes. The cause of aging, according to an increasing amount of research, is chromosomal instability which weakens the structure of these chromosomes. It has been identified as a major cause of aging because it leads to a decline in protein quality. Chromosomal instability is intensified by mutational load – where DNA mutations are accumulated over time. Mutational loads are thought to lead to many issues related with the aging process including changes in muscle tissue.
A study in Telomere Shortening
Telomeres, the ends of chromosomes, are also the subject of biological aging research. Telomeres are a type of telomere that is known to be impacted by aging. Chromosomes go through the replication process many times during the course of their lives. Telomeres are gradually shortened during the replication process. With time, their mending process becomes less effective, resulting in shortening. Telomerase is the enzyme in charge of repairing telomeres, but it can’t keep up with the rate of telomere deterioration. As a result, the researchers attempted to determine a person’s biological age using chromosomal health. It’s still unclear how the length of telomeres affects aging. The rate of telomere shortening has a high association with the lifetime of different species, according to recent studies.
Senescent cells and their role in aging
Does cellular senescence hold secrets for healthier aging?
Cells experience aging, just as humans do. Senescent cells burden the human body when they accumulate and the exact mechanism triggering senescence is not known.
The phenomenon that telomeres shorten with age is linked to aging. One cause of shortening in the telomere is the cell senescence. The following diagram shows how cell senescence can shorten telomeres:
Quantifying the process of cell senescence and studying its impact on the body can reveal interesting information about how our bodies ages. This process is being developed by scientists, according to recent studies. Scientists are expected to be able to track biological aging with this new method in the near future.
Mitochondrial Health
A mitochondrion is an important cell component of the human body because it provides energy and helps to regulate bodily functions. Even more importantly, when it starts to decline in strength, mitochondria play a role in aging. The anti-aging result has shown that taking supplements of NAD precursors improves mitochondrial function in the cells and helps improve energy levels.
Vascular Health
Scientists can measure biological age by looking at factors such as the state of blood vessels. This can help to better understand how fast a person is aging. The interleukins, protein-based indicators, and DNA mutations in the blood can allow for measurement of vascular health.
DNA Methyl Groups
Scientists have found a way to measure which includes measuring the DNA methyl groups that are accumulated in a person. This is because higher amounts indicates an increased risk of disease, thus helping you diagnose when to take preventative measures.
How to Reverse Aging?
Biological aging can be measured as newer research is being done to study the process. Anti-aging research is promising among those who want to go against aging, and it has led them to some discoveries, like increasing amounts of NAD+ and getting rid of senescent cells.
It is crucial for NAD+ levels to be high in humans because it declines with age and this causes a range of health problems, such as cancer, diabetes, and osteoporosis. It is imperative that the cells’ mitochondria are functioning properly, so the NAD+ level in the body must be regulated to ensure that SIRT1 is activated.
Several scientists have been looking for different ways to increase NAD+ levels in cells so that humans can avoid all the diseases associated with aging. Trials still need to be carried out but research so far looks promising and some scientists claim that it is possible to reverse the effects of aging.
Knowing what causes the majority of age-related disorders, scientists have been experimenting with several NAD+ precursors to boost NAD+ levels in human cells. Taking supplements of NAD+ precursors like NMN and NR has been proven to improve defense against aging in a variety of organisms. Human experiments are still being conducted, but the research appears to be promising. In his best-selling book “Lifespan: Why We Age – and Why We Don’t Have To,” David Sinclair, a major researcher in the anti-aging area, claims that it is feasible to not only slow down but also reverse aging. All of this is made possible by replacing our body’s diminishing levels of NAD+.
Other than that, Resveratrol can be effective in fighting aging, while Fisetin removes senescent cells. The most important anti-aging discovery to date has been NAD+ and it is possible that taking NAD+ supplements may reverse aging.
Related Products
Following our discussion of biological aging and reading about how aging can be slowed or reversed, it’s time to see what the industry has to offer in terms of items that correspond to our discussion.
LIPO NAD+ Complete – Powdered Liposomal NAD+, NMN, & NR
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Renue By Science’s Lipo NAD+ Complete contains all three NAD+ boosters, NAD+, NMN, and NR. The substance is available in powdered liposomal form. Liposomal transport of substances to our circulation and tissues is a novel method of keeping vitamins and medications intact in the hostile environment of our stomach, ensuring that the real product is not harmed during consumption. It improves bioavailability and makes the substance more effective at low doses.
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Tru Niagen® 300mg
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The goal of Tru Niagen is to increase NAD+ levels in the body, which is thought to halt or reverse the aging process. One of the constituents in the Tru Niagen supplement is nicotinamide riboside chloride, which when consumed is transformed into NAD+.
Tru Niagen is one of the most effective supplements for increasing NAD levels. However, it is not only incredibly efficient, but it is also quite safe. In reality, using Tru Niagen has little – if any – negative effects. Most users tolerate it exceedingly well, and clinical tests have shown that it is safe.
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NAD+ Cell Regenerator™ and Resveratrol
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Life Extension’s Best in Class formula for energy support, NAD+ Cell RegeneratorTM and Resveratrol. Every dosage contains a strong 300 mg of NIAGEN® nicotinamide riboside and trans-resveratrol.
NIAGEN® nicotinamide riboside raises NAD+ levels in the body. Resveratrol promotes the healthy expression of genes associated with lifespan. They’ve combined the two to create a new dietary supplement that increases metabolic activity compatible with longevity, maintains healthy cellular metabolism, modifies the expression of genes linked with some elements of the aging process, and much more.
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EAT VARIOUS NUTRIENT-DENSITY WHOLE FOODS
Blood sugar dysregulation and inflammation are now known to be two of the leading causes of aging. As a result, we’d like to tailor our diets to address these issues. This necessitates consuming a large amount of nutrient-dense whole meals.
These meals are extremely beneficial to the health of our skin. They also aid a process known as methylation, which is necessary for a variety of bodily activities.
Include a wide variety of complete foods in your diet, such as folate-rich cruciferous vegetables, sulphur-containing foods (leeks, onions, garlic, etc.) to aid liver detoxification, and a rainbow of colorful fruits and vegetables, such as berries.
These foods are strong in polyphenols, which are powerful antioxidants that nourish the good bacteria in our stomachs and lower oxidative stress in the body, protecting us from diseases like Alzheimer’s, type 2 diabetes, cancer, and heart disease.
Also, foods containing sirtuin-activating chemicals should be avoided. These substances aid in the activation of our longevity genes as well as the improvement of our metabolism. Raw cacao, ECGC from green tea, curcumin from turmeric, and resveratrol from red wine are just a few examples.
To build muscular tissue, skin health, and neurotransmitters, combine these plant-based diets with nutritious proteins. Our muscle mass starts to drop around the age of 30, so we need to make sure we’re consuming enough protein to compensate.
If you eat meat, look for grass-fed, pasture-raised meats and fatty fish. Eggs can help with methylation and brain function.
Exercise
It has been proven that thirty minutes of moderate exercise five times a week can greatly increase our lifespan. Moderate indicates you can still talk, but not as easily as if you were sitting motionless. A good example would be taking a brisk stroll.
Dr. Kara Fitzgerald’s recent research discovered that combining moderate exercise with a 12-hour overnight fast and a diet rich in methylation- and sirtuin-enhancing substances truly reverses biological ageing. And surprisingly swiftly – individuals were able to reduce their biological age by an average of 3.5 years over the eight-week research.
The Carol smart bike offers custom HIIT workouts- That’s the future of fitness without question!
Create Your Dream Fitness Retreat With These 22 Best Home Gym Brands From A To Z
FASTING
Many of us graze on a frequent basis throughout the day without even realizing it. Even if the snacks are healthful, eating on a regular basis means our digestive systems never get a rest.
Everyone fast for at least 12 hours overnight unless they have a medical reason not to (such as type 1 diabetes). This entails eating your last meal earlier and your first meal later to allow your digestive system to rest and repair.
Many factors influence whether or not you should fast for longer than 12 hours, including your stress level, age, and hormone levels. Many research on fasting for longer periods of time have been conducted on obese, sedentary men.
It’s usually better for women’s hormones to keep the fasting period to 12-14 hours overnight. This allows the body to heal itself and keeps insulin sensitivity in check.
ProLon gives you reset in just 5 days by providing the benefits of fasting without having to skip a meal!
The ProLon® Fasting Mimicking Diet® is the only 5-day dietary program shown through clinical trials to nourish your body while triggering the natural process of cellular clean-up and rejuvenation associated with fasting. Users typically experience greater energy and focus, better sleep, a slimmer waistline, and an improvement in their relationship with food, finding themselves satisfied with smaller portions and experiencing less cravings.
ProLon® meals come in 5 small boxes (one for each day) that include plant-based energy bars, soups, a variety of snacks, drinks, and supplements, all studied and carefully designed to nourish your body while keeping it in a fasting state for benefits from the inside out.
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SLEEP
Sleep is so important for slowing down the aging process, yet it’s also something that many of us struggle to prioritize. Regular readers will already be aware of the importance of sleep for your skin — it’s for a reason that people talk about getting their beauty sleep!
When you’re in your 40s, the only time you create significant amounts of human growth hormone is when you’re sleeping deeply. This hormone is responsible for a variety of functions, including muscular growth, skin rejuvenation, and gut lining repair.
Having a good circadian rhythm and sleep routine is one of the best things you can do for your longevity. Every day, try to go to bed and wake up at the same time.
Because insulin inhibits the creation of human growth hormone, it’s best not to eat too close to bedtime. Make your last meal three to four hours before bedtime.
Sleep & Metabolic Well being: How Sleep Can Enhance Your Day-to-Day
REDUCE STRESS
Because stress causes us to age, we need to make sure we have a variety of tools at our disposal to assist us manage our stress and find peace.
If you’ve been following me for a while, you’ll know that one of the main goals of my Face Yoga and facial massage routines is to relieve stress and tension. Taking a few minutes each day to focus on self-care can make a significant difference in your stress levels.
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