Huang Lian Jie Du Wan for acute infectious disease

Table of contents

Traditional therapeutic uses

Main indications: Infectious disease in the acute phase, otitis, urinary tract infection, respiratory infection, dysentery, boils and abscesses.

In Chinese energy, this formula is used against the toxic Heat which clogs the three Foci.

Associated symptoms : high fever, dry mouth and throat, dark urine, restlessness and irritability, red tongue with a yellow coating, broad, fast and strong pulse

Dosage

As this formula is found in different forms and at different concentrations, it is important to follow the manufacturer's recommendations. Do not exceed the recommended dosage. Cannot be used long term.

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It is the standard formula to fight against all infections regardless of the infectious agent, whether localized (otitis, abscess, etc.) or generalized (spreads its toxins throughout the body). This formula should be used in the acute stages of the disease: high fever, dark urine. Several plants have an antibiotic action. Savoy, the main ingredient, has demonstrated an action in vitro and in vivo against : Streptococcus pneumoniae, Neisseria menigitidis, Staphylocccus aureus, Shigella dysenteriae, Shigella sonnei, Pseudomonas aeruginosa, Salmonella paratyphi, Mycobacterium, virusesinfluenza, Hemophilus pertussis, the Leptospiras. The Savoy also has a febrifuge and anti-inflammatory action. The plants of the formula attack microbes on several fronts and do not generate resistance to treatment like antibiotics do.

Historical

This formula is cited in the Wai Tai Bi Yao, The essentials of the imperial bookstore, a work written by Wang Tao in 752 CE.

Research

A study carried out on rats contaminated with endotoxins, showed that Huang Lian Jie Du Tang (the same formula in the form of a decoction rather than in pills) lowers the fever.¹

According to three studies done on mice, Huang Lian Jie Du Tang has an antioxidant action on the brain², an anti-inflammatory action on certain neurons³ and a protective action in cases of weakened memory and learning ability following a stroke.⁴

Cons-indications

This formula can hurt Yin, so it should not be taken for a long time. It is very bitter and refreshing and contains no invigorating plants. It is suitable for people of robust constitution.

Composition

Name in pine yin	Pharmaceutical name	Therapeutic actions
Huang Lian	Rhizoma coptidis (Savoyan rhizome)	Chases away Heat, drains Moisture, natural antibiotic effective against viruses, bacteria, fungi and yeasts.
Huang Qin	Radix scutellariae (skullcap root)	Drains Heat and Moisture, natural antibiotic effective against viruses and bacteria.
Huang Bai	Cortex Phellodendri (phellodendron bark)	Cools the Heat, eliminates toxins.
Zhi Zi	Fructus gardeniae jasminoidis (gardenia fruit)	Drains Heat and Moisture from Liver and Gallbladder.

On the shelves

The products of the following companies meet the good manufacturing practices of theAustralian Therapeutic Goods Administration, which are currently regarded as the highest standards in the world for the evaluation of the manufacturing processes of products from the Chinese Pharmacopoeia.
As these brands are generally reserved for practitioners of traditional Chinese medicine, they may not be found over the counter and may have to be obtained from an acupuncturist or a health professional.

	Huang Lian Jie Du Teapills. Mark : Plum Flower, made in China for Mayway Corporation, Oakland (CA), USA.
	Huang Lian Jie Du Wan. Mark : Herbal Times, made in China for Nuherbs Co., Oakland (CA), USA.

Available from distributors of acupuncture equipment and traditional Chinese medicine.

Research and writing: Arlette Rouleau, Ac., OAQ and Pierre Lefrançois

References

Bensky Dan and Barolet Randall, Chinese Herbal Medicine, Formulas & Strategies, Seattle, Eastland Press, 1990.
Fratkin Jake Paul, Chinese Herbal Patent Medicines, Shya Publications, Boulder, July 2001.
Brother Marie-Victorin. Laurentian flora, Montreal, Les Presses com l'Université com Montréal, 1964.
Married Eric. Large Chinese Pharmacopoeia form, Editions Paracelse, 1990.
Naeser Margaret A. Outline Guide to Chinese Herbal Patent Medicines in Pill Form, Boston, Boston Chinese Medicine, 1993.

1. TAN, Y.Z., PENG, D.M., XIAO, S. L., LONG, M.H., and HU, Y. M. Effects of nine prescriptions on fever in rats induced by endotoxin, Chung Kuo Chung Yao Tsa Chih, flight. 14, no 5, 1989, pp. 306-7, 305, 320.
2. Fushitani S, Minakuchi K, Tsuchiya K, Takasugi M, Murakami K .. (Studies on attenuation of post-ischemic brain injury by kampo medicines-inhibitory effects of free radical production. II). (in Japanese, summary in English). Yakugaku Zasshi August 1995, 115 (8): 611-7.
3. DAI, Y., MIKI, K., FUKUOKA, T., TOKUNAGA, A., TACHIBANA, T., KONDO, E., ET NOGUCHI, K., Suppression of neuropeptides' mRNA expression by herbal medicines in a rat model of peripheral inflammation, Life Sci, 2000; 66 (1): 19-29.
4. XU, J., MURAKAMI, Y., MATSUMOTO, K., TOHDA, M., WATANABE, H., ZHANG, H., YU, O., and SHEN, J., Protective effect of Oren-gedoku- to (Huang-Lian-Jie-Du-Tang) against impairment of learning and memory induced by transient cerebral ischemia in mice, J Ethnopharmacol. December 2000, 73 (3): 405-13.

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